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Immune Cells in Ovarian Cancer May Help Predict Survival

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Stromal Tumor infiltrating lymphocytes (sTILs) as a prognostic biomarker in Ovarian Cancer After Neoadjuvant chemotherapy.

Doctors are learning more about how the immune system affects cancer.

A new study looked at immune cells called stromal tumor-infiltrating lymphocytes (sTILs) in women with high-grade serous ovarian cancer.

These are immune cells found near the cancer in the tissue.

The women in the study had chemotherapy first, followed by surgery to remove as much cancer as possible.

Some also had a special heated treatment in the belly called HIPEC. After surgery, their cancer tissue was tested to see how many immune cells were present.

The study found that when more immune cells were found in the ovary—at least 20%—women lived longer.

These results stayed strong even when other factors were considered.

A similar finding was seen with immune cells in the omentum (a layer of fat in the belly), where a 26% cutoff was used.

This means that checking for immune cells in ovarian cancer tissue after treatment might help doctors predict which patients will do better. It could help guide future treatment decisions.

More research is needed to confirm the exact numbers, but these early results are promising.

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