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Radiation After Surgery May Help High-Risk Stomach Cancer Patients Stay Cancer-Free Longer

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Radiation After Surgery May Help High-Risk Stomach Cancer Patients Stay Cancer-Free Longer

A new study has found that for certain patients with stomach cancer, adding radiation therapy after surgery may improve their chances of staying cancer-free.

Researchers studied 312 patients with gastric cancer who had undergone a type of extensive surgery called D2 gastrectomy. After surgery, patients were randomly placed into two groups: one received chemotherapy alone, and the other received chemotherapy followed by radiation therapy (called chemoradiation).

Overall, there was no major difference between the two groups in terms of survival without cancer at three years. But when researchers looked more closely, they found that patients with higher-risk cancer—those with more lymph node involvement—benefited more from the added radiation.

In this high-risk group, about 71% of patients who received chemoradiation were cancer-free after three years, compared to only 53% in the chemotherapy-only group. This is a significant improvement.

Side effects from treatment were similar between the groups, with no major differences in serious complications.

These results suggest that for patients with high-risk stomach cancer, radiation therapy after surgery and chemotherapy could offer better long-term outcomes. It might not be necessary for everyone, but for those at greater risk, it could make a big difference.

If you’ve had surgery for gastric cancer, ask your oncologist whether adding radiation to your treatment plan is right for you—especially if your cancer involved many lymph nodes.

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